Research Supported by the Foundation

Supporting scientific research is the centerpiece of Marilyn Brachman Hoffman’s legacy. Here you will find publications which emerged from research funded by the Foundation and more information about our research initiatives.

  • Effects of the COVID-19 pandemic on individuals with chemical intolerance

    Palmer RF, Kattari D, Verduzco-Gutierrez M. Effects of the COVID-19 pandemic on individuals with chemical intolerance. Family Med Community Health. 2025;13(2):e003081. Published 2025 Apr 24. doi:10.1136/fmch-2024-003081

    Health Associations

    2025

  • Heart rate variability is not associated with multiple chemical sensitivity in a cross-sectional population-based study - The Danish study of functional disorders

    Bjerregaard AA, Brinth L, Petersen MW, et al. Heart rate variability is not associated with multiple chemical sensitivity in a cross-sectional population-based study - The Danish study of functional disorders. J Psychosom Res. 2025;188:111992. doi:10.1016/j.jpsychores.2024.111992

    Causes & Mechanisms

    2025

  • Multiple chemical sensitivity (MCS) validity, prevalence, tools and interventions: systematic review protocol

    Hempel S, Zhang D, Robinson KA, et al. Multiple chemical sensitivity (MCS) validity, prevalence, tools and interventions: systematic review protocol. BMJ Open. 2025;15(5):e088136. Published 2025 May 8. doi:10.1136/bmjopen-2024-088136

    Reviews & Evidence

    2025

  • Assessing Chemical Intolerance in Parents Predicts the Risk of Autism and ADHD in Their Children

    Palmer RF, Kattari D, Rincon R, Miller CS. Assessing Chemical Intolerance in Parents Predicts the Risk of Autism and ADHD in Their Children. J Xenobiot. 2024;14(1):350-367. Published 2024 Mar 5. doi:10.3390/jox14010022

    Health Associations

    2024

  • Clinical assessment and patient education of chemical intolerance

    Ravi T, Johnson-Esparza Y, Hernandez J, Andry N, Ali F, Del Pilar Montanez Villacampa M, Rincon R, Perales R, & Palmer RF. Clinical assessment and patient education of chemical intolerance.International Journal of Community Medicine and Public Health. 2024 Feb 6. https://doi.org/10.18203/2394-6040.ijcmph20240310.

    Screening & Assessment

    2024

  • Diabetes Quality of Life, Chemical Intolerance, and Generational Status in a Latino Sample: An RRNeT Study

    Johnson-Esparza Y, Wood R, Cruz I, Palmer RF,  Diabetes Quality of Life, Chemical Intolerance, and Generational Status in a Latino Sample: An RRNeT Study. Journal of Diabetes and Metabolic Disorders. (2024). https://doi.org/10.1007/s40200-023-01374-3

    Health Associations

    2024

  • Environmental house calls can reduce symptoms of chemical intolerance: a demonstration of personalized exposure medicine

    Rincón R, Perales R, Palmer RF, et al. Environmental house calls can reduce symptoms of chemical intolerance: a demonstration of personalized exposure medicine. Primary Health Care Research & Development. 2024;25:e53. doi:10.1017/S146342362400046X

    Environmental & Clinical Care

    2024

  • Fluctuation of functional somatic disorders in a population-based cohort. The DanFunD study

    Schovsbo SU, Kårhus LL, Bjerregaard AA, et al. Fluctuation of functional somatic disorders in a population-based cohort. The DanFunD study.PLoS One. 2024;19(10):e0312031. Published 2024 Oct 16. doi:10.1371/journal.pone.0312031

    Population & Risk Factors

    2024

  • Lifestyle factors as predictors of incident functional somatic disorder

    JØrgensen T, Jacobsen RK, Weinreich Petersen M, et al. Lifestyle factors as predictors of incident functional somatic disorder. Five-year follow-up of The DanFunD study. Scand J Public Health. Published online October 22, 2024. doi:10.1177/14034948241283545

    Population & Risk Factors

    2024

  • Multiple Chemical Sensitivity: An Evidence Map

    Zhang D, Danz M, Robinson K, Espinosa-Wade E, Berry N, Brahmbhatt N, Sysawang K, Yagyu S, Motala A, Tolentino D, Akbari O, Johnston J, Hempel S. (2024). Multiple Chemical Sensitivity: An Evidence Map. Society of General Internal Medicine California-Hawaii Regional Meeting, San Francisco, CA, January 2024, DOI: 10.13140/RG.2.2.15856.47361

    Reviews & Evidence

    2024

  • Chemical Intolerance and Mast Cell Activation: A Suspicious

    Palmer RF, Dempsey TT, Afrin LB. Chemical Intolerance and Mast Cell Activation: A Suspicious Synchronicity. Journal of Xenobiotics. 2023 Nov 12;13(4):704-718. doi: 10.3390/jox13040045. PMID: 37987446; PMCID: PMC10660865.

    Causes & Mechanisms

    2023

  • A genome-wide SNP investigation of chemical intolerance

    Palmer, R.F., Almeida, M., Perales, R.B., Rincon, R. D. (2023). A genome-wide SNP investigation of chemical intolerance.Environmental Advances, 12, art. no. 100380. DOI: 10.1016/j.envadv.2023.100380

    Causes & Mechanisms

    2023

  • Multiple chemical sensitivity scoping review protocol: overview of research and MCS construct

    Hempel S, Danz M, Robinson KA, Bolshakova M, Rodriguez J, Mears A, Pham C, Yagyu S, Motala A, Tolentino D, Akbari O, Johnston J. Multiple chemical sensitivity scoping review protocol: overview of research and MCS construct.BMJ Open. 2023 Sep 22;13(9):e072098. doi: 10.1136/bmjopen-2023-072098. PMID: 37739463; PMCID: PMC10533706.

    Reviews & Evidence

    2023

  • Social economic factors and at the risk of multiple chemical sensitivity in a Danish population-based cross-sectional study: Danish Study of Functional Disorders (DanFunD)

    Ahrendt Bjerregaard A, Schovsbo SU, Gormsen LK, Skovbjerg S, Eplov LF, Linneberg A, Cedeño-Laurent JG, Jørgensen T, Dantoft TM. (2023). Social economic factors and at the risk of multiple chemical sensitivity in a Danish population-based cross-sectional study: Danish Study of Functional Disorders (DanFunD). BMJ Open, 13(3), e066037. http://dx.doi.org/10.1136/bmjopen-2022-064618

    Population & Risk Factors

    2023

  • What initiates chemical intolerance? Findings from a large population-based survey of U.S. adults

    Miller, C.S., Palmer, R.F., Kattari, D. et al. What initiates chemical intolerance? Findings from a large population-based survey of U.S. adults. Environmental Sciences Europe 35, 65 (2023). https://doi.org/10.1186/s12302-023-00772-x

    Causes & Mechanisms

    2023

  • Association between infections and functional somatic disorders: a cross-sectional population-based cohort study

    Schovsbo, S. U., Møllehave, L. T., Petersen, M. W., Ahrendt Bjerregaard, A., Eliasen, M., Pedersen, S. B., Eplov, L. F., Kårhus, L. L., Fink, P., Linneberg, A., Dantoft, T. M., Jørgensen, T., & Benros, M. E. (2022). Association between infections and functional somatic disorders: a cross-sectional population-based cohort study. BMJ Open, 12(11), e066037. https://doi.org/10.1136/bmjopen-2022-066037

    Health Associations

    2022

  • The Brief Environmental Exposure and Sensitivity Inventory (BREESI): an international validation study.

    Palmer, R.F., Rincon, R., Perales, R.B. et al. The Brief Environmental Exposure and Sensitivity Inventory (BREESI): an international validation study. Environ Sci Eur(34)32 (2022). https://doi.org/10.1186/s12302-022-00600-8

    Screening & Assessment

    2022

  • Does Improving Indoor Air Quality Lessen Symptoms Associated with Chemical Intolerance?

    Perales RB, Palmer RF, Rincon R, Viramontes JN, Walker T, Jaén CR, Miller CS. (2022). Does Improving Indoor Air Quality Lessen Symptoms Associated with Chemical Intolerance? Primary Health Care Research and Development 23(e3), 1. https://doi.org/10.1017/S1463423621000864

    Environmental & Clinical Care

    2022

  • Multiple Chemical Sensitivity

    Hempel S, Danz M, Robinson KA, Bolshakova M, Imasuen E, Rodriguez J, Mears, A, Pham C, Yagyu S, Motala A, Tolentino D, Akbari O, Johnston J. (2022). Multiple Chemical Sensitivity. osf.io/4a3wu.

    Reviews & Evidence

    2022

  • Physiological Health and Physical Performance in Multiple Chemical Sensitivity-Described in the General Population

    Bjerregaard, A. A., Petersen, M. W., Skovbjerg, S., Gormsen, L. K., Cedeño-Laurent, J. G., Jørgensen, T., Linneberg, A., & Dantoft, T. M. (2022). Physiological Health and Physical Performance in Multiple Chemical Sensitivity-Described in the General Population. International journal of environmental research and public health, 19(15), 9039. https://doi.org/10.3390/ijerph19159039

    Health Associations

    2022

  • Validation of a Brief Screening Instrument for Chemical Intolerance in a Large U.S. National Sample

    Palmer RF, Walker T, Kattari D, Rincon R, Perales RB, Jaén CR, Grimes C, Sundblad DR, Miller CS. (2021). Validation of a Brief Screening Instrument for Chemical Intolerance in a Large U.S. National Sample.International Journal of Environmental Research and Public Health. 18(16), 8714. https://doi.org/10.3390/ijerph18168714

    Screening & Assessment

    2021

  • Mast Cell Activation May Explain Many Cases of Chemical Intolerance

    Miller CS, Palmer RF, Dempsey T, Ashford N, Afrin LB. (2021). Mast Cell Activation May Explain Many Cases of Chemical Intolerance. Environmental Sciences Europe 33(129). https://doi.org/10.1186/s12302-021-00570-3

    Causes & Mechanisms

    2021

  • Insulin Resistance Is Associated with Multiple Chemical Sensitivity in a Danish Population-Based Study-DanFunD

    Bjerregaard, A. A., Petersen, M. W., Gormsen, L. K., Skovbjerg, S., Jørgensen, N. R., Linneberg, A., Cedeño-Laurent, J. G., Jørgensen, T., & Dantoft, T. M. (2021). Insulin Resistance Is Associated with Multiple Chemical Sensitivity in a Danish Population-Based Study-DanFunD. International Journal of Environmental Research and Public Health, 18(23), 12654. https://doi.org/10.3390/ijerph182312654

    Health Associations

    2021

  • Disease Comorbidities Associated with Chemical Intolerance

    Palmer RF, Walker T, Perales RB, , Rincon R, Jaén CR, Miller CS (2021). Disease Comorbidities Associated with Chemical Intolerance.Environmental Disease 6(4), 134-141. doi: 10.4103/ed.ed_18_21

    Health Associations

    2021

  • Toxicant-induced loss of tolerance for chemicals, foods, and drugs: assessing patterns of exposure behind a global phenomenon

    Masri S, Miller CS, Palmer RF, Ashford N. (2021). Toxicant-induced loss of tolerance for chemicals, foods, and drugs: assessing patterns of exposure behind a global phenomenon. Environmental Sciences Europe 33(65). https://doi.org/10.1186/s12302-021-00504-z

    Causes & Mechanisms

    2021

  • Three questions for identifying chemically intolerant individuals in clinical and epidemiological populations: The Brief Environmental Exposure and Sensitivity Inventory (BREESI)

    Palmer RF, Jaén CR, Perales RB, Rincon R, Forster JN, Miller CS. (2020.) Three questions for identifying chemically intolerant individuals in clinical and epidemiological populations: The Brief Environmental Exposure and Sensitivity Inventory (BREESI)PLoS ONE 15(9): e0238296. https://doi.org/10.1371/journal.pone.0238296

    Screening & Assessment

    2020

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